When I meet with the founders of a new company, my advice is almost always, 'Do fewer things.' It's true of partnerships, marketing opportunities, anything that's taking up your time. The vast majority of things are distractions, and very few really matter to your success.

I suspect there’s a lot of validity to the premise that big companies aren’t going to attract entrepreneurial talent.

News in general doesn’t matter most of the time, and most people would be far better off if they spent their time consuming less news and more ideas that have more lasting import.

I tried to be a ski bum when I stepped away from Twitter, and I wasn’t a very good skier.

Take care of yourself: When you don’t sleep, eat crap, don’t exercise, and are living off adrenaline for too long, your performance suffers. Your decisions suffer. Your company suffers. Love those close to you: Failure of your company is not failure in life. Failure in your relationship is.

User experience is everything. It always has been, but it’s undervalued and underinvested in. If you don’t know user-centered design, study it. Hire people who know it. Obsess over it. Live and breathe it. Get your whole company on board.

Hard things are valuable; easy things are not so valuable. Reaching the mountaintop is rewarding because it is hard. If it was easy, everybody would do it.

Take care of yourself: When you don't sleep, eat crap, don't exercise, and are living off adrenaline for too long, your performance suffers. Your decisions suffer. Your company suffers. Love those close to you: Failure of your company is not failure in life. Failure in your relationship is.

News in general doesn't matter most of the time, and most people would be far better off if they spent their time consuming less news and more ideas that have more lasting import.

The vast majority of things are distractions, and very few really matter to your success.